Is This The Definitive Cure For Cancer? Two Girls Cured By “Gene Editing”

Imagine discovering that your child had cancer – what would you do?

It’s a terrible thing for any parent to have to face, but the decisions that the parents of two children being treated at Great Ormond Street hospital for cancer made may have repercussions for all of us when it comes to cancer treatment in the future.

The two girls, Layla and another who wishes to remain anonymous, nearly died and if hadn’t been for a brand new form of therapy, they almost certainly would have died. Here’s what you need to know about their heart-wrenching tale battling a fearsome disease.

10. Cancer Treatment Is Spotty At Best

Layla was just a year old when she was diagnosed with leukemia. Leukemia is a cancer which regularly affects children and is often fatal if it cannot be treated effectively. Yet there are only two options when it comes to conventional treatment: radiotherapy and chemotherapy, and both have their drawbacks.

9. Layla Was Dying

Layla was dying. Her young body simply could not stand the chemotherapy or radiotherapy that would be required. These treatments attack the cancer, but also attack the body of the host. She was too weak and too sick to survive the treatments. Her parents were desperate, and time was running out for her.

8. An Emerging Form Of Treatment

Doctors at Layla’s hospital suggested Immunotherapy. Immunotherapy is an emerging form of cancer treatment. The idea is simple – you work with the body’s own immune system to get the body to remove cancer. Layla’s mom said, “We didn’t want to give up on our daughter, though, so we asked the doctors to try anything.”

7. A Virus That Kills Cancer

CAR-T Cell Therapy is what they proposed to try with Layla. It works by using a virus to change the genetic code of the body’s T-cells. T-cells are a major part of our immune system. Altering T-cells through CAR-T Cell Therapy enables them to recognize the cancerous cells in the body and to attack them.

6. A Living Drug

The doctors working on CAR-T Cell Therapy say it is a “living drug.” They told Layla’s family that CAR-T Cell Therapy is “much more potent than anything we can achieve” with other forms of immunotherapy.
“It was scary to think the treatment had never been used in a human before,” said Layla’s father Ashleigh, “but there was no doubt we wanted to try the treatment. She was sick and in lots of pain, so we had to do something.”